|
KMID : 0380619910230030370
|
|
Korean Journal of Food Science and Technology
1991 Volume.23 No. 3 p.370 ~ p.374
|
|
|
Inhibitory Effects of Garlic on the Mutagenicity in Salmonella Assay System and on the Growth of HT - 29 Human Colon Carcinoma Cells
|
|
김소희/Kim, So Hee
박건영/정해영/서명자/Park, Kun Young/Chung, Hae Young/Suh, Myung Ja
|
|
|
Abstract
|
|
|
|
The inhibitory effects of garlic on the mutagenicity in Salmonella assay system and on the growth of HT-29 human colon carcinoma cells were studied. Methanol extract of garlic inhibited the mutagenicities induced by aflatoxin B₁(AFB₁) and N-methyl-N´-nitro-N-nitrosoguanidine(MNNG) in Salmonella typhimurium TA100. The inhibition rate increased significantly when the concentration of the methanol extract from garlic increased in both strains of Salmonella typhimurium TA98 and TA100. The chloroform fraction from the methanol extract exhibited strong antimutagenicity against AFB,. The chloroform fraction also inhibited greatly the growth of human HT-29 colon carcinoma cells in fetal bovine serum concentrations of 1% and 5%.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|